Jessica Smith Selected Research

Insulin Receptor

1/2021	Endothelial Insulin Receptors Promote VEGF-A Signaling via ERK1/2 and Sprouting Angiogenesis.
9/2013	Endothelium-specific insulin resistance leads to accelerated atherosclerosis in areas with disturbed flow patterns: a role for reactive oxygen species.
4/2012	Increasing circulating IGFBP1 levels improves insulin sensitivity, promotes nitric oxide production, lowers blood pressure, and protects against atherosclerosis.
8/2011	The insulin-like growth factor-1 receptor is a negative regulator of nitric oxide bioavailability and insulin sensitivity in the endothelium.

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Jessica Smith Research Topics

Disease

10	Insulin Resistance 09/2014 - 12/2007
7	COVID-19 01/2024 - 01/2021
6	Neoplasms (Cancer) 01/2023 - 01/2015
5	Infections 01/2024 - 01/2021
5	Obesity 01/2021 - 05/2005
4	Cardiovascular Diseases (Cardiovascular Disease) 01/2020 - 04/2006
3	Weight Loss (Weight Reduction) 01/2023 - 02/2011
3	Atherosclerosis 01/2020 - 04/2012
3	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 11/2006 - 05/2005
2	Cystitis 01/2024 - 12/2023
2	Wounds and Injuries (Trauma) 01/2023 - 10/2009
2	Premature Birth (Birth, Premature) 10/2022 - 01/2013
2	Neonatal Abstinence Syndrome 03/2022 - 01/2022
2	Ischemia 01/2021 - 01/2020
2	Cardiomyopathies (Cardiomyopathy) 03/2020 - 12/2017
2	Thrombosis (Thrombus) 02/2020 - 03/2012
2	Chronic Pain 12/2019 - 01/2018
2	Thyroiditis 01/2019 - 11/2007
2	Overweight 11/2014 - 04/2009
2	Abdominal Obesity 10/2013 - 04/2006
2	Dyslipidemias (Dyslipidemia) 10/2013 - 06/2012
2	Inflammation (Inflammations) 01/2012 - 08/2011
2	Morbid Obesity 04/2011 - 02/2011
1	Soft Tissue Infections 12/2023
1	Supratentorial Neoplasms 01/2023
1	Burns 01/2023
1	Brain Neoplasms (Brain Tumor) 01/2023
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 10/2022
1	Neuralgia (Stump Neuralgia) 01/2022
1	Substance Withdrawal Syndrome (Withdrawal Symptoms) 01/2022
1	Central Nervous System Vascular Malformations (Dural Arteriovenous Fistula) 01/2022
1	Coinfection 01/2022
1	Shock 09/2021
1	Pneumonia (Pneumonitis) 09/2021
1	Lung Neoplasms (Lung Cancer) 01/2021
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2021
1	Multiple Myeloma 01/2021
1	Communicable Diseases (Infectious Diseases) 12/2020
1	Heart Failure 03/2020
1	Hemorrhage 02/2020
1	Gastroesophageal Reflux (GERD) 01/2020

Drug/Important Bio-Agent (IBA)

7	Insulin (Novolin)FDA Link 01/2020 - 12/2007
5	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2020 - 08/2011
4	Insulin ReceptorIBA 01/2021 - 08/2011
4	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 02/2012
4	LipidsIBA 11/2014 - 09/2006
3	Hormones (Hormone)IBA 01/2021 - 04/2011
3	AntibodiesIBA 10/2019 - 11/2007
3	AdiponectinIBA 11/2014 - 05/2005
3	des-Arg-(77)- complement C3aIBA 04/2009 - 05/2005
2	nasIBA 03/2022 - 01/2022
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2022 - 08/2019
2	CytokinesIBA 01/2021 - 01/2012
2	Amyloid (Amyloid Fibrils)IBA 03/2020 - 12/2017
2	Antisense OligonucleotidesIBA 03/2020 - 12/2017
2	Prealbumin (Transthyretin)IBA 03/2020 - 12/2017
2	Thyrotropin (Thyroid-Stimulating Hormone)FDA Link 01/2019 - 11/2007
2	Antithyroid Agents (Antithyroid Drugs)IBA 01/2019 - 11/2007
2	HDL CholesterolIBA 10/2013 - 06/2012
2	Reactive Oxygen Species (Oxygen Radicals)IBA 09/2013 - 06/2013
2	Apolipoproteins E (ApoE)IBA 09/2013 - 04/2012
2	IGF Type 1 Receptor (IGF 1 Receptor)IBA 09/2012 - 08/2011
2	Triglycerides (Triacylglycerol)IBA 06/2012 - 12/2007
2	Thyrotropin Receptors (Thyrotropin Receptor)IBA 12/2009 - 11/2007
2	Complement C3 (C3 Complement)IBA 12/2007 - 05/2005
2	Sirolimus (Rapamycin)FDA Link 11/2006 - 10/2005
2	Eukaryotic Initiation Factor-4EIBA 11/2006 - 02/2005
2	Apolipoproteins B (ApoB)IBA 09/2006 - 04/2006
2	70-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA 10/2005 - 02/2005
2	Interferon-alpha (Interferon Alfa)IBA 10/2005 - 05/2005
1	Fentanyl (Sublimaze)FDA LinkGeneric 12/2023
1	Levetiracetam (Keppra)FDA LinkGeneric 01/2023
1	CR3022IBA 01/2023
1	Monomeric GTP-Binding ProteinsIBA 10/2022
1	AntigensIBA 10/2022
1	incobotulinumtoxinA FDA Link 01/2022
1	Methadone (Dolophine)FDA LinkGeneric 01/2022
1	Type A Botulinum Toxins (Botox)FDA Link 01/2022
1	VaccinesIBA 10/2021
1	InterleukinsIBA 01/2021
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 01/2021
1	Interleukin-33IBA 01/2021
1	InotersenIBA 03/2020
1	Adenosine Diphosphate (ADP)IBA 02/2020
1	Insulin-Like Growth Factor Binding Protein 1IBA 01/2020
1	Insulin-Like Growth Factor Binding ProteinsIBA 01/2020

Therapy/Procedure

13	Therapeutics 12/2023 - 11/2007
4	Radiotherapy 01/2024 - 01/2021
4	Critical Care (Surgical Intensive Care) 01/2021 - 10/2009
4	Gastric Bypass (Roux-en-Y Gastric Bypass) 01/2020 - 02/2011
3	Exercise Therapy (Therapy, Exercise) 01/2024 - 01/2021
3	Bariatric Surgery 01/2023 - 01/2020
2	Cervical Cerclage 10/2022 - 01/2013
2	Pain Management 12/2019 - 01/2018
1	Lasers (Laser) 01/2023
1	Craniotomy 01/2023
1	Duration of Therapy 01/2023
1	Terminal Care (Care, Terminal) 10/2022
1	Anesthesia 09/2021
1	Gastrectomy 01/2020